Ergot derivatives like methyl ergometrine maleate, commonly used to promote uterine contractions postpartum, can rarely induce severe coronary artery spasm leading to acute myocardial infarction, necessitating careful monitoring.
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Alerts to rare ergot-induced coronary spasm postpartum; leaves open incidence and risk stratification in larger cohorts.
We report a primigravida woman with acute myocardial infarction caused by coronary artery spasm induced by intravenous administration of methyl ergometrine maleate just after delivery. Despite the frequent usage of ergot derivatives to promote uterine contractions, cardiac complications related to this drug are rare. Myocardial infarction may be overlooked in young women in the early postpartum period. Careful monitoring and prompt evaluation should be performed when this drug is administered for obstetrical purposes.
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Hayashi et al. (2003) studied this question.
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