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July 10, 2009European Journal of Cardio-Thoracic SurgeryOpen Access

Risk factors of atrial fibrillation following off-pump coronary artery bypass graft surgery: predictive value of C-reactive protein and transfusion requirement

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Key result

Packed red blood cell transfusion was a strong independent predictor of postoperative atrial fibrillation following off-pump coronary bypass surgery (OR 5.32; 95% CI 2.80-10.11; p<0.001).

Population

315 consecutive patients with normal sinus rhythm undergoing elective isolated off-pump coronary bypass…

Design

Cohort

Follow-up

6 postoperative days

Authors

YCYong Seon ChoiYonsei UniversityJSJae‐Kwang ShimYonsei UniversitySHSeong Wook HongKyungpook National University

Discussion

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Implication

May warrant caution with transfusions in off-pump CABG; leaves open whether association is causal or modifiable.

Study Design

Type

Cohort (n=315)

Structured PICO

P
Population
315 consecutive patients with normal sinus rhythm undergoing elective isolated off-pump coronary bypass surgery, monitored for 6 postoperative days.
E
Exposure
Risk factors including high-sensitive C-reactive protein (hsCRP) levels, packed red blood cells (pRBCs) transfusion, vasopressor therapy, and low LVEF (<30%)
O
Outcome
Development of postoperative atrial fibrillation (AF) during the first 6 postoperative dayshard clinical

Main Result

Odds Ratio: 5.32 (95% CI 2.8–10.11)

p-value: p=<0.001

Packed red blood cell transfusion, low LVEF, vasopressor use, and elevated hsCRP are independent predictors of postoperative atrial fibrillation following off-pump CABG.

Cite This Study

Choi et al. (2009) conducted a cohort in undergoing elective isolated off-pump coronary bypass surgery (OPCAB) (n=315). Packed red blood cells (pRBCs) transfusion was evaluated on postoperative atrial fibrillation (AF) (OR 5.32, 95% CI 2.80-10.11, p=<0.001). Packed red blood cell transfusion was a strong independent predictor of postoperative atrial fibrillation following off-pump coronary bypass surgery (OR 5.32; 95% CI 2.80-10.11; p<0.001).

synapsesocial.com/papers/6a99c7742a60c81fa4abfb56https://doi.org/10.1016/j.ejcts.2009.05.003

Topics

Atrial fibrillationPersistent AF managementAnticoagulation in AFAF ablation outcomes
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Also Consider

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  1. 1Atrial fibrillation following coronary artery bypass graft surgery: predictors, outcomes, and resource utilization. MultiCenter Study of Perioperative Ischemia Research Group1996 · 741 citations
  2. 2ACC/AHA/ESC 2006 guidelines for the management of patients with atrial fibrillation–executive summary. A report of the American College of Cardiology/American Heart Association Task Force on practice guidelines and the European Society of Cardiology Committee for Practice Guidelines (Writing Committee to Revise the 2001 Guidelines for the Management of Patients with Atrial Fibrillation)2007 · 185 citations
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