Key result
A proposed computational model of strain-induced cardiac growth, modulated by wall strains and shear stresses, resulted in physiologically reasonable tissue growth during embryonic development.
A novel computational model suggests that strain-induced growth, rather than stress-induced growth, better explains embryonic cardiovascular development and highlights the role of mechanical coupling.
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No immediate clinical relevance; leaves open validation of strain-induced cardiac growth models in translational settings.
Sandra Rugonyi (2013) studied Embryonic Cardiovascular Development. Strain-induced growth model vs. Stress-induced growth models was evaluated on Tissue growth and remodeling. A proposed computational model of strain-induced cardiac growth, modulated by wall strains and shear stresses, resulted in physiologically reasonable tissue growth during embryonic development.
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