Key result
Cardiac lupus can be rapidly progressive and have severe consequences unless treated early with high-level immunosuppression.
Case Report (n=1)
Systemic lupus-related cardiomyopathy can be rapidly progressive and requires early, high-level immunosuppression.
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May prompt early high-level immunosuppression in cardiac lupus; case report leaves open need for prospective validation.
Background. We present the case of a 35-year-old gentleman who presented with an aggressive cardiomyopathy with normal coronary arteries. He was later diagnosed with systemic lupus-related cardiomyopathy. Methods. We undertook an extensive review of the literature regarding cardiac manifestations of lupus and used over 100 journals to identify the key points in pathology, diagnosis, and treatment. Results. We have shown that cardiac lupus can be rapidly progressive and, unless treated early, can have severe consequences. The predominant pathologies are immune complex and accelerated atherosclerosis drive. Treatment comprised of high-level immunosuppression.
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Ashrafi et al. (2011) conducted a case report in Systemic lupus-related cardiomyopathy (n=1). High-level immunosuppression was evaluated. Cardiac lupus can be rapidly progressive and have severe consequences unless treated early with high-level immunosuppression.
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