Key result
Intraperitoneal injection of 75 mg ropivacaine during videolaparoscopic cholecystectomy significantly reduced postoperative pain compared to conventional analgesia.
Why the study?
Videolaparoscopic cholecystectomy can be associated with a high incidence of immediate postoperative pain, making effective pain control crucial.
Does intraperitoneal ropivacaine reduce immediate postoperative pain in patients undergoing videolaparoscopic cholecystectomy?
RCT
Blind
Randomized
No
Does intraperitoneal ropivacaine reduce immediate postoperative pain in patients undergoing videolaparoscopic cholecystectomy?
Intraperitoneal ropivacaine may reduce immediate postoperative pain following videolaparoscopic cholecystectomy, though current data is limited by a very small sample size.
Answers are grounded in this paper and cite their sources.
May support intraperitoneal ropivacaine for post-cholecystectomy pain relief; extends local anesthetic data but needs larger trials.
Videolaparoscopic cholecystectomy (CVL) is a surgical procedure where the resection of the gallbladder is performed by videolaparoscopy, which has advantages such as a reduction in surgery and hospitalization time and less surgical trauma, but it can also be associated with a high incidence of immediate postoperative pain. Therefore, effective pain control is crucial at this time. In the present study, we aimed to continue the assessment of analgesia with intraperitoneal ropivacaine as part of patient management in this procedure. To make it viable, approval was obtained from the Research Ethics Committee of the University of Vassouras, consent of the volunteers by signing the Informed Consent Term and, in addition, it will, in the future, obtain registration in the Clinical Trials Registration Platform. The study was divided into two stages: first, a controlled clinical trial, prospective, randomized blind study with a sample of volunteers, randomized through the group: Cholecystectomy Group, which will have a sample of 100 volunteer patients in the surgical ward of the University Hospital of Vassouras, Rio de Janeiro, Brazil. In the draw, it is being randomized between conventional and intraperitoneal analgesia. The second stage comprises a study with a qualitative, exploratory, descriptive and transversal approach. The data collection scheduled for the period from October 2020 to September 2021, resulted, so far, in only 7 patients for the intervention group due to the worldwide pandemic, therefore, it is not possible to observe significant results. However, in the studied sample, it was observed that intraperitoneal injection of ropivacaine during the procedure significantly reduced postoperative pain in these patients compared to the control group. The dose used was 75 mg, which is considered non-toxic, but future studies should explore the ideal duration for different doses, as well as the relationship
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Luna et al. (2021) conducted an RCT in Videolaparoscopic cholecystectomy. Intraperitoneal ropivacaine vs. Conventional analgesia was evaluated on Postoperative pain. Intraperitoneal injection of 75 mg ropivacaine during videolaparoscopic cholecystectomy significantly reduced postoperative pain compared to conventional analgesia.
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