Key result
Significant joint hypermobility was found in 63% of ASD patients aged 2-4 years and 73% aged ≥5 years, with no significant correlation to cognitive impairment or autism severity (p>0.05).
Why the study?
A link between ASD and joint hypermobility is rarely established in clinical settings, and their relationship has not been completely investigated across all age groups of children with ASD.
Is joint hypermobility associated with cognitive impairment and autism severity in children with autism spectrum disorder?
Cohort (n=67)
Is joint hypermobility associated with cognitive impairment and autism severity in children with autism spectrum disorder?
p-value: p=> 0.05
Joint hypermobility is highly prevalent in children with ASD but does not appear to correlate with the severity of autism or cognitive impairment.
Hypermobility screening may aid musculoskeletal care in ASD without altering cognitive or severity evaluations; leaves open causal links for prospective study.
Autism spectrum disorder (ASD) and joint hypermobility (JH) are considered two different etiological and clinical entities that most often appear in childhood. Despite growing increased research showing a co-occurrence for both conditions, a link between them is rarely established in clinical settings, and the relationship between ASD and JH has not so far been completely investigated in all age groups of ASD children. This preliminary study examined a cohort of 67 non-syndromic ASD children aged 2–18 years (sex ratio M:F = 12:1) showing different degrees of cognitive impairment and autism severity, using the Beighton scale and its revised version. A total of 63% of ASD patients aged 2–4 years and 73% of ASD patients aged ≥5 years presented significant scores of hypermobility. No significant correlation was found comparing total laxity score and cognitive assessments and severity of autistic symptomatology (p > 0.05). The results suggest that JH could be considered as a clinical characteristic of ASD patients and it needs to be assessed in order to schedule a better rehabilitation program.
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Romeo et al. (2023) conducted a cohort in Autism spectrum disorder (n=67). Autism spectrum disorder was evaluated on Correlation between total laxity score and cognitive assessments and severity of autistic symptomatology (p=> 0.05). Significant joint hypermobility was found in 63% of ASD patients aged 2-4 years and 73% aged ≥5 years, with no significant correlation to cognitive impairment or autism severity (p>0.05).
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