Key result
Exposure of sugar beet vacuoles to K+ malate activated instantaneous and time-dependent outward currents by positive membrane potentials, which were 10 times more selective for malate than K+.
Population
Vacuoles from sugar beet (Beta vulgaris) cell suspensions
Design
Preclinical
Authors
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No immediate clinical implications; leaves open analogous malate-selective channels in mammalian systems.
Time-dependent outward channels could serve as the route for malate movement into the vacuole, while K+ moves through time-independent channels.
Pantoja et al. (1992) studied this question. K+ malate and KCl was evaluated on Electrical properties of vacuoles (activation of instantaneous and time-dependent outward currents). Exposure of sugar beet vacuoles to K+ malate activated instantaneous and time-dependent outward currents by positive membrane potentials, which were 10 times more selective for malate than K+.
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