Key result
Antiplatelet agents in diabetic patients after amputation for gangrene yielded negative overall results, with suggestive findings in cerebrovascular disease and sudden death subgroups.
Why the study?
Do antiplatelet agents improve outcomes in diabetic patients after amputation for gangrene?
Population
Diabetic patients after amputation for gangrene
Design
Review
Authors
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Negative overall results advise against routine use; leaves open cerebrovascular and sudden death subgroup effects for future study.
Do antiplatelet agents improve outcomes in diabetic patients after amputation for gangrene?
This review of a negative VA trial of antiplatelet agents in diabetic amputees discusses methodological challenges and potential subgroup effects.
Colwell et al. (2009) conducted a review in Diabetic patients after amputation for gangrene. Antiplatelet Agents was evaluated. Antiplatelet agents in diabetic patients after amputation for gangrene yielded negative overall results, with suggestive findings in cerebrovascular disease and sudden death subgroups.
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