Use of Arterial Transfer Functions for the Derivation of Central Aortic Waveform Characteristics in Subjects With Type 2 Diabetes and Cardiovascular Disease

We refer to the letters of Wilkinson and McEniery (1) and Avolio, Cockcroft, and O’Rourke (2). In our article, we make it abundantly clear that all results, including the transfer function utilized, were generated from data obtained in our laboratory (3). As the above correspondents note, we have previously reported at length in peer-reviewed literature how this is implemented by our group (4–9). There is no published data to support the contention that any transfer function performs adequately in subjects with diabetes (10–13). This issue has not been addressed in the literature by enthusiasts of …