What question did this study set out to answer?

To examine testosterone, vitamin D, bone mineral density, and semen quality and determine their relationships in fertile and infertile men.

June 19, 2012International Journal of AndrologyOpen Access

Associations between testosterone, bone mineral density, vitamin D and semen quality in fertile and infertile Chinese men

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Authors

BYBo YangDurham University HSHang SunNational Institute for Parasitic Diseases YWYi WanJiangnan University

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Implication

Cross-sectional study observes reduced testosterone and bone density in infertile men, suggesting shared endocrine pathways regulate skeletal and reproductive health.

Key Points

To examine testosterone, vitamin D, bone mineral density, and semen quality and determine their relationships in fertile and infertile men.
Assessed 559 Chinese men aged 20–40 years, comprising 195 fertile controls, 9 infertile men with known osteoporosis risk factors, and 355 infertile men without known osteoporosis risk factors.
Categorized infertile men without osteoporosis risk factors into 314 oligo-, astheno-, terato-, or normospermic men and 41 non-obstructive azoospermic men.
Evaluated serum testosterone, 25-hydroxyvitamin D, lumbar spine and total hip bone mineral density, and semen parameters using multiple linear regression.
Infertile men without osteoporosis risk factors exhibited significantly lower testosterone, lumbar spine bone mineral density, and total hip bone mineral density compared to fertile men (all p < 0.05).
Bioavailable testosterone and 25-hydroxyvitamin D were independent determinants of bone mineral density in infertile men without risk factors (all p < 0.01), with significantly lower bone density occurring at bioavailable testosterone ≤ 11.6 nmol/L (p < 0.05).
In infertile men, 25-hydroxyvitamin D independently determined sperm motility and morphology (all p < 0.05), while testosterone determined sperm concentration and morphology (all p < 0.001).

Cite This Study

Yang et al. (2012) studied this question.

synapsesocial.com/papers/6a99d950c6616c1e40abfeb7 https://doi.org/10.1111/j.1365-2605.2012.01287.x

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Implication

Cross-sectional study observes reduced testosterone and bone density in infertile men, suggesting shared endocrine pathways regulate skeletal and reproductive health.

Associations between testosterone, bone mineral density, vitamin D and semen quality in fertile and infertile Chinese men

Discussion

Member takes

Implication

Key Points

Cite This Study

Associations between testosterone, bone mineral density, vitamin D and semen quality in fertile and infertile Chinese men

Discussion

Member takes

Implication

Key Points

Cite This Study

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