Key result
Aggressive perioperative control of blood glucose (<150 mg/dl) using insulin is suggested to decrease cardiovascular mortality for patients with diabetes undergoing surgery.
Design
Review
Authors
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May support insulin-based perioperative glucose control in diabetes; hypothesis-generating and requires randomized confirmation before practice change.
This review highlights the critical role of tight glycemic control in reducing cardiovascular mortality during acute myocardial infarction and perioperative periods, while cautioning against the use of sulfonylureas which may abolish ischemic preconditioning.
Gu et al. (2003) conducted a review in Diabetes Mellitus. Aggressive perioperative glycemic control was evaluated. Aggressive perioperative control of blood glucose (<150 mg/dl) using insulin is suggested to decrease cardiovascular mortality for patients with diabetes undergoing surgery.
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