Key result
Higher phase angle linked to ~38% lower risk of cognitive impairment in older CVD patients.
Why the study?
Reliable biomarkers for the early detection of cognitive decline in older adults with CVD are lacking, and phase angle may serve as a novel tool.
Does phase angle (PhA) predict cognitive impairment in older adults with cardiovascular disease?
Cross-Sectional (n=340)
Does phase angle (PhA) predict cognitive impairment in older adults with cardiovascular disease?
Odds Ratio: 0.62 (95% CI 0.43–0.89)
p-value: p=0.01
Reduced phase angle is independently associated with cognitive impairment in older adults with cardiovascular disease, highlighting its potential as a noninvasive screening biomarker.
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PhA may aid cognitive screening in older CVD patients; cross-sectional data leave open predictive value and require prospective validation.
Huan et al. (2025) conducted a cross-sectional in Cardiovascular Disease and Cognitive Impairment (n=340). Phase angle (PhA) vs. Higher phase angle was evaluated on Cognitive impairment (OR 0.62, 95% CI 0.43-0.89, p=0.01). Reduced phase angle is independently associated with an increased risk of cognitive impairment in older patients with cardiovascular disease (OR 0.62).
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