Key result
Outpatient oral anticoagulation with warfarin was safe in children, with no thrombotic complications and infrequent haemorrhagic events (2.1% of visits).
Why the study?
What are the dose requirements, efficacy of INR control, and complication rates of oral anticoagulation in pediatric patients?
Population
45 children aged 9 months to 18 years, the majority receiving primary prophylactic anticoagulation. Main…
Design
Cohort
Follow-up
602 patient months
Authors
Loading...
Supports outpatient warfarin in children; hypothesis-generating for dosing and requires RCTs before practice change.
Cohort (n=45)
What are the dose requirements, efficacy of INR control, and complication rates of oral anticoagulation in pediatric patients?
Outpatient oral anticoagulation with warfarin is feasible and safe in pediatric patients, with dose requirements moderately predictable based on weight and age.
Tait et al. (1996) conducted a cohort in Congenital heart disease (n=45). Oral anticoagulation (warfarin) was evaluated on Target international normalised ratios (INRs) achievement and complications. Outpatient oral anticoagulation with warfarin was safe in children, with no thrombotic complications and infrequent haemorrhagic events (2.1% of visits).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: