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June 2, 2009Circulation

Associations of Physical Activity With Inflammatory Factors, Adipocytokines, and Metabolic Syndrome in Middle-Aged and Older Chinese People

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Key result

Higher levels of total physical activity were associated with a lower risk of metabolic syndrome (OR 0.68; 95% CI 0.54 to 0.85; P for trend=0.001) among middle-aged and older Chinese adults.

Why the study?

Does higher physical activity improve inflammatory factors, adipocytokines, and reduce metabolic syndrome in middle-aged and older Chinese people?

Population

3289 individuals 50 to 70 years of age from a population-based cross-sectional survey in Beijing and…

Comparison

Higher levels of total physical activity vs Lower levels of total physical activity

Design

Cross-sectional

Authors

ZYZhijie YuDalhousie UniversityXYXingwang YeInner Mongolia Electric Power (China)JWJing WangHangzhou Normal University

Discussion

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Implication

Supports observational link of higher activity with lower metabolic syndrome risk; hypothesis-generating for interventions in middle-aged Chinese adults.

Study Design

Type

Cross-Sectional (n=3,289)

Multicenter

Yes

Structured PICO

Does higher physical activity improve inflammatory factors, adipocytokines, and reduce metabolic syndrome in middle-aged and older Chinese people?

P
Population
3,289 middle-aged and older Chinese adults (50-70 years) assessed for physical activity, inflammatory factors, and metabolic syndrome.
E
Exposure
Higher levels of total physical activity (assessed with the International Physical Activity Questionnaire)
C
Comparator
Lower levels of total physical activity
O
Outcome
Levels of inflammatory factors (high-sensitivity C-reactive protein, interleukin-6, tumor necrosis factor-alpha receptor 2), adipocytokines (adiponectin, retinol-binding protein 4), and presence of metabolic syndromesurrogate

Main Result

Odds Ratio: 0.68 (95% CI 0.54–0.85)

p-value: p=0.001

Higher physical activity is associated with a better inflammatory and adipocytokine profile and a reduced risk of metabolic syndrome in middle-aged and older Chinese adults.

Cite This Study

Yu et al. (2009) conducted a cross-sectional in Metabolic syndrome (n=3,289). Higher levels of total physical activity vs. Lower levels of total physical activity was evaluated on Metabolic syndrome (OR 0.68, 95% CI 0.54 to 0.85, p=0.001). Higher levels of total physical activity were associated with a lower risk of metabolic syndrome (OR 0.68; 95% CI 0.54 to 0.85; P for trend=0.001) among middle-aged and older Chinese adults.

synapsesocial.com/papers/6a99e0462a60c81fa4ac056fhttps://doi.org/10.1161/circulationaha.108.833574

Topics

Women and heart disease
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Physical activity and public health. A recommendation from the Centers for Disease Control and Prevention and the American College of Sports Medicine1995 · 7,014 citations
  2. 2Adiponectin and Metabolic Syndrome in Middle‐aged and Elderly Chinese2008 · 59 citations
  3. 3Diagnosis and Management of the Metabolic Syndrome2005 · 11,934 citations
  4. 4Physical Activity and Hemostatic and Inflammatory Variables in Elderly Men2002 · 460 citations
  5. 5Reliability and Validity of the IPAQ-Chinese2008 · 334 citations