Key result
Pregnancy in women with repaired Tetralogy of Fallot was complicated by cardiac events in 17.5% of deliveries, and was associated with persistent right ventricular enlargement at 6 months postpartum.
Why the study?
Does pregnancy increase the risk of cardiac events and right heart dilation in women with repaired tetralogy of Fallot?
Population
25 pregnant women with repaired tetralogy of Fallot who had a total of 40 deliveries, mean age at delivery…
Design
Cohort
Follow-up
up to 1 year after delivery
Authors
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May inform preconception counseling for repaired TOF; extends observational data on postpartum RV changes but leaves causal effects open.
Cohort (n=25)
No
Does pregnancy increase the risk of cardiac events and right heart dilation in women with repaired tetralogy of Fallot?
Pregnancy in women with repaired tetralogy of Fallot is generally successful but carries a 17.5% risk of cardiac events, which are predicted by prior ablation and enlarged cardiothoracic ratio, and may lead to persistent right ventricular dilation.
Kamiya et al. (2012) conducted a cohort in Repaired Tetralogy of Fallot in pregnancy (n=25). Pregnancy vs. Pre-pregnancy baseline / Uncomplicated pregnancies was evaluated on Pregnancy-associated cardiac events (arrhythmia, heart failure, endocarditis, or thromboembolic events). Pregnancy in women with repaired Tetralogy of Fallot was complicated by cardiac events in 17.5% of deliveries, and was associated with persistent right ventricular enlargement at 6 months postpartum.
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