Key result
Experimental inoculation with FMDV caused severe clinical disease and transmission in bison, whereas elk developed only mild lesions and did not transmit the virus to cattle.
Population
North American bison (Bison bison), elk (Cervus elaphus nelsoni), and cattle
Comparison
Intraepithelial tongue inoculation with 10,000… vs Unexposed contact animals
Design
Preclinical
Follow-up
28 days postinfection
Authors
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Bison warrant heightened FMD surveillance near livestock; leaves open elk's transmission risk pending field validation.
Bison are highly susceptible to FMDV and can transmit it to cattle, whereas elk show mild signs and poor transmission capability.
Rhyan et al. (2008) studied Foot-and-mouth disease. FMDV, strain O1 Manisa inoculation vs. Unexposed contact animals was evaluated on Susceptibility, clinical signs, and transmission of FMDV. Experimental inoculation with FMDV caused severe clinical disease and transmission in bison, whereas elk developed only mild lesions and did not transmit the virus to cattle.
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