Key result
Carbonic anhydrase activity in the bowfin swimbladder was comparable to air-breathing organs of teleosts, and bowfin blood plasma lacked endogenous CA inhibitors.
The absence of endogenous CA inhibitors in bowfin blood plasma contrasts with teleostean fishes and may have phylogenetic implications.
No clinical implications for CA inhibitor use; leaves open phylogenetic significance of absent plasma inhibitors versus teleosts.
Carbonic anhydrase (CA) activity was measured in the respiratory swimbladder, gill filaments and red blood cells of the primitive air‐breathing holostean fish, the bowfin, Amia calva. The activity of swimbladder CA, relative to gill and red cell CA activities, was within the range reported previously for unimodally‐breathing fishes and was comparable to the CA activities reported for the air‐breathing organs of teleosts. It is unlikely that carbon dioxide excretion across the bowfin swimbladder is limited to the uncatalyzed rate of HCO3‐dehydration. Bowfin blood plasma lacked any endogenous inhibitor(s) of CA, in contrast with information on teleostean fishes. This absence may have interesting phylogenetic implications and may offer some potential for investigating the nature and physiological role of plasma CA inhibitors.
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Heming et al. (1986) studied this question. Carbonic anhydrase activity measurement was evaluated on Carbonic anhydrase (CA) activity in swimbladder, gills, and red blood cells. Carbonic anhydrase activity in the bowfin swimbladder was comparable to air-breathing organs of teleosts, and bowfin blood plasma lacked endogenous CA inhibitors.
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