Experimental study demonstrates high-yield synthesis of benzofuran and indole derivatives from quinones and silyl enol ethers, suggesting an efficient catalytic pathway for heterocyclic compounds.
In the presence of a catalytic amount of trityl perchlorate, 1,4-benzoquinone, quinone monoimides, or imidoquinones react with silyl enol ethers to produce the corresponding benzofuran or indole derivatives in high yields via the corresponding Michael adducts.
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Mukaiyama et al. (1987) studied this question.
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