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Shows that hydrogenosomes in the parasite Tritrichomonas foetus contain cardiolipin, indicating an endosymbiotic origin linked to bacteria and mitochondria.
Hydrogenosomes are found in organisms that lack typical mitochondria. Cardiolipin is a phospholipid located exclusively in bacterial membranes and the inner membrane of mitochondria. Here we show, by cell fractionation, thin-layer chromatography, high-pressure liquid chromatography, and matrix-assisted laser desorption ionization-time of flight mass spectrometry that hydrogenosomes of Tritrichomonas foetus, a cattle vaginal parasite, contain cardiolipin, which is strong evidence for its endosymbiotic origin.
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Rosa et al. (2006) studied this question.
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