Key result
Presence of type 2 diabetes at baseline was associated with significantly smaller weight loss at 2 years following bariatric surgery compared to patients without diabetes (change in BMI -13.7 vs -16.4 kg/m2).
Why the study?
It was unclear whether baseline type 2 diabetes and post-surgical diabetes remission affect weight loss outcomes following bariatric surgery.
Does the presence of type 2 diabetes at baseline reduce weight loss following bariatric surgery in morbidly obese patients?
Population
312 consecutive morbidly obese subjects undergoing bariatric surgery
Comparison
Baseline T2D vs no T2D, and T2D remitters vs non-remitters
Design
Observational cohort study
Follow-up
Up to 5 years
Authors
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Baseline T2D may attenuate bariatric weight loss; leaves open whether remission or glycemic factors modify response.
Cohort (n=312)
No
Does the presence of type 2 diabetes at baseline reduce weight loss following bariatric surgery in morbidly obese patients?
Absolute Event Rate: -13.7% vs -16.4%
p-value: p=0.0006
Patients with type 2 diabetes, especially those who do not achieve remission, experience significantly less weight loss following bariatric surgery compared to patients without diabetes.
Rebelos et al. (2022) conducted a cohort in Morbid obesity (n=312). Type 2 diabetes vs. Absence of type 2 diabetes was evaluated on Change in BMI at 2 years (p=0.0006). Presence of type 2 diabetes at baseline was associated with significantly smaller weight loss at 2 years following bariatric surgery compared to patients without diabetes (change in BMI -13.7 vs -16.4 kg/m2).
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