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July 15, 2020PLoS ONEOpen Access

The rational use of thromboprophylaxis therapy in hospitalized patients and the perspectives of health care providers in Northern Cyprus

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Key result

Among 180 hospitalized patients, 47.7% received irrational thromboprophylaxis management, and surveys revealed insufficient knowledge of DVT risk assessments and prophylaxis among healthcare providers.

Why the study?

Despite standard guidelines, many hospitalized patients at risk of thromboembolism do not receive prophylaxis or receive it irrationally, leading to unwanted side effects.

Population

180 hospitalized patients in general wards of two tertiary university hospitals and healthcare providers

Comparison

Rational vs irrational DVT prophylaxis based on Caprini risk assessment tool

Design

Observational study and cross-sectional survey

Follow-up

Two weeks post-hospitalization

Authors

SSSyed Sikandar ShahAAAbdikarim AbdiBÖBarçın Özcem

Discussion

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Member takes

Overview

Provider knowledge gaps may drive irrational DVT prophylaxis; Level 3 data leaves open whether education improves outcomes in trials.

Study Design

Type

Observational (n=180)

Multicenter

Yes

Structured PICO

P
Population
180 acute and chronically ill hospitalized adult patients at risk of deep vein thrombosis, followed for two weeks post-hospitalization to assess the rational use of thromboprophylaxis.
E
Exposure
Thromboprophylaxis (most commonly enoxaparin) evaluated for rationality using the Caprini risk assessment tool.
O
Outcome
Rational use of DVT prophylaxis and assessment of health care providers' knowledge and attitudes regarding DVT prevention.

A high proportion of hospitalized patients receive irrational DVT prophylaxis, highlighting a significant gap in health care provider knowledge and practice regarding VTE prevention.

Limitations

  • Only 2 teaching hospitals were chosen as the study setting, limiting generalizability to non-teaching hospitals.
  • Demographic data of the physicians were not collected to increase the response rate.
  • Unable to properly document pulmonary embolism as the cause of death for patients who died during hospitalization.

Cite This Study

Shah et al. (2020) conducted an observational in Hospitalized patients at risk of deep vein thrombosis (n=180). Thromboprophylaxis management was evaluated on Proportion of patients receiving rational thromboprophylaxis management. Among 180 hospitalized patients, 47.7% received irrational thromboprophylaxis management, and surveys revealed insufficient knowledge of DVT risk assessments and prophylaxis among healthcare providers.

synapsesocial.com/papers/6a99ea3a2a60c81fa4ac0a1bhttps://doi.org/10.1371/journal.pone.0235495
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The Epidemiology of Venous Thromboembolism2003 · 2,323 citations
  2. 2Lifestyle interventions for the treatment of women with gestational diabetes2017 · 287 citations
  3. 3Deep vein thrombosis: pathogenesis, diagnosis, and medical management2017 · 390 citations
  4. 4Comparison between Caprini and Padua risk assessment models for hospitalized medical patients at risk for venous thromboembolism: a retrospective study2016 · 69 citations
  5. 5Compliance with current VTE prophylaxis guidelines and risk factors linked to complications of VTE prophylaxis in medical inpatients: a prospective cohort study in a Spanish internal medicine department2018 · 10 citations