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May 1, 2018BMJ OpenOpen Access

Compliance with current VTE prophylaxis guidelines and risk factors linked to complications of VTE prophylaxis in medical inpatients: a prospective cohort study in a Spanish internal medicine department

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Why the study?

What is the degree of compliance with VTE prophylaxis guidelines and what are the risk factors for prophylaxis-related complications in elderly hospitalised medical patients?

Population

396 hospitalised, elderly medical patients who did not undergo surgery, had no active or previous oral…

Design

Cohort

Follow-up

during admission

Authors

INIgnacio Novo‐VeleiroLALucía Alvela-SuárezACAlba Costa‐Grille

Discussion

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Overview

High compliance does not eliminate hematoma risk in elderly inpatients; hypothesis-generating for personalized VTE prophylaxis strategies.

Structured PICO

What is the degree of compliance with VTE prophylaxis guidelines and what are the risk factors for prophylaxis-related complications in elderly hospitalised medical patients?

P
Population
396 hospitalised, elderly medical patients who did not undergo surgery, had no active or previous oral anticoagulation or low molecular weight heparin (LMWH) treatment during the previous year, and received VTE prophylaxis during admission.
I
Intervention
Venous thromboembolism (VTE) prophylaxis during admission
O
Outcome
Degree of compliance with current guidelines (estimated by PADOVA and IMPROVE indexes) and development of complications (major and minor bleeding, major and minor haematoma, and decrease of platelet count)safety

Complications during VTE prophylaxis in elderly medical inpatients are frequent despite correct guideline application, with major haematomas strongly linked to obesity, concomitant antiplatelet therapy, and enoxaparin use.

Cite This Study

Novo‐Veleiro et al. (2018) studied this question.

synapsesocial.com/papers/69fd5301ea4a61241c5d1aaahttps://doi.org/10.1136/bmjopen-2017-021288
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