Key result
A simulation system originally developed for mechanical heart assist devices was modified and presented for in vitro testing of intra-aortic balloon pump hemodynamics and energetics.
An in vitro test bench was successfully adapted to simulate and analyze the short-term hemodynamic and energetic effects of IABP assistance.
Enables in vitro IABP hemodynamic testing in adapted simulators; leaves open clinical translation without in vivo validation.
IABP assistance is frequently used to support heart recovery, improving coronary circulation and re-establishing the balance between oxygen availability and consumption. Hemodynamic and energetic parameters (endocardial viability ratio, ventricular energetics) are used to evaluate its effectiveness which depends on internal (timing, balloon volume and position) and external factors (circulatory conditions). Considering short, medium and long-term effects of IABP, the first depends on its mechanical action, the latter on the changes induced in circulatory parameters. The analysis of the first is important because conditions for the onset of a virtuous cycle able to support ventricular recovery are created. Simulation systems could be helpful in this analysis for the implicit reliability and reproducibility of the experiments, provided that they are able to reproduce both hemodynamic phenomena and energetic relationships. The aim of this paper is to present a system originally developed to test mechanical heart assist devices and modified for IABP testing. Data reported here are obtained from in vitro experiments. A partial verification, obtained from the literature is presented.
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Ferrari et al. (2001) studied this question. Intra-aortic balloon pump (IABP) testing system was evaluated. A simulation system originally developed for mechanical heart assist devices was modified and presented for in vitro testing of intra-aortic balloon pump hemodynamics and energetics.
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