Key result
Sustained extracellular activation of cat motoneurons yielded a mean firing duration of 123 ± 88 s for F cells and 233 ± 19 s for S cells, significantly longer than intracellular stimulation.
Population
Spinal motoneurons supplying the medial gastrocnemius muscle of deeply anaesthetized cats
Design
Preclinical
Authors
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Does not yet alter clinical motor control approaches; leaves open translation of extracellular mechanisms to human models.
Absolute Event Rate: 123% vs 233%
Extracellular stimulation of cat motoneurons reveals significantly longer firing durations compared to previously reported intracellular stimulation, with S cells exhibiting longer sustained firing than F cells.
Spielmann et al. (1993) studied this question. Sustained extracellular activation vs. S cells (vs F cells) was evaluated on Mean firing duration in response to 240 s of sustained activation. Sustained extracellular activation of cat motoneurons yielded a mean firing duration of 123 ± 88 s for F cells and 233 ± 19 s for S cells, significantly longer than intracellular stimulation.
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