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The process of diffusion of fluid in porous media and biological membranes has usually been modelled with Darcy's constitutive equation, which states that the flux is proportional to the pressure gradient. However, when the permeability of the matrix changes during the process, solution of the equations governing the diffusion presents severe analytical difficulties because the variation of permeability is not known a priori.
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Caputo et al. (2004) studied this question.
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