Transscleral Intraocular Lens Fixation with Preservation of the Anterior Vitreous Face in Patients with Marfan Syndrome and Ectopia Lentis

PURPOSE: To evaluate the safety and efficacy of transscleral intraocular lens fixation with preservation of the anterior vitreous in the treatment of ectopia lentis in patients with Marfan syndrome. METHODS: Patients who had undergone surgical intervention for ectopia lentis with or without lenticular opacity were included. Best-corrected visual acuity before and after surgery was compared. Perioperative complications were evaluated. RESULTS: A total of 23 patients (45 eyes) whose mean age at surgery was 16.9 ± 8.9 years were recruited. The mean follow-up period was 10.1 ± 5.8 months. Mean best-corrected visual acuity change (with respect to preoperative logarithm of the minimum angle of resolution value) was 1.03 ± 0.39. All patients showed >2 lines of improvement in visual acuity. Pupillary capture was found in 6 eyes. Medically controllable intraocular pressure elevation was noted in 12 eyes. CONCLUSION: Transscleral intraocular lens fixation with preservation of the anterior vitreous face is a safe and effective technique for treatment of ectopia lentis in patients with Marfan syndrome.