Key result
Patients with typical angina had significantly poorer physical functioning and higher anxiety levels compared to those with other chest pain types, while HRQoL did not differ based on the presence of obstructive CAD.
Why the study?
HRQoL is impaired in patients with stable angina, but patients often present with other forms of chest pain, leaving pre-diagnostic HRQoL across angina types, gender, and obstructive CAD uncharacterized.
Cross-Sectional (n=1,263)
Yes
Absolute Event Rate: 41.2% vs 43.3%
p-value: p=<0.01
In patients with stable chest pain referred for diagnostic evaluation, pre-diagnostic health-related quality of life is associated with chest pain characteristics and gender, but not with the actual presence of obstructive coronary artery disease.
No takes yet. Share an insight, caveat, or question.
HRQoL in stable chest pain links to symptoms and gender, not CAD; hypothesis-generating and should not yet change practice.
Rieckmann et al. (2020) conducted a cross-sectional in Suspected coronary artery disease with stable chest pain (n=1,263). Typical angina vs. Atypical angina, non-anginal chest discomfort, or other chest discomfort was evaluated on SF-12 physical component score (p=<0.01). Patients with typical angina had significantly poorer physical functioning and higher anxiety levels compared to those with other chest pain types, while HRQoL did not differ based on the presence of obstructive CAD.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: