Key result
Pregnancies in women with a Fontan circulation resulted in a 54.8% miscarriage rate, with high rates of preterm delivery (72.2%) and postpartum haemorrhage (42.6%) among those with live births.
Cohort (n=50)
Yes
Women with a Fontan circulation have a high rate of miscarriage (54.8%) and significant obstetric and neonatal complications, with maternal hypoxemia (<85% saturation) strongly predicting pregnancy loss.
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Supports risk stratification by oxygen saturation in Fontan pregnancies; leaves open whether interventions targeting hypoxemia reduce miscarriage.
Cauldwell et al. (2017) conducted a cohort in Pregnancy in women with a Fontan repair (n=50). Fontan circulation was evaluated on Miscarriage. Pregnancies in women with a Fontan circulation resulted in a 54.8% miscarriage rate, with high rates of preterm delivery (72.2%) and postpartum haemorrhage (42.6%) among those with live births.
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