Key result
Periprocedural myocardial injury following TAVR was associated with a significantly increased risk of 30-day all-cause mortality (OR 4.23; 95% CI 1.95-9.19; P<0.001).
Why the study?
Does periprocedural myocardial injury predict mortality and adverse events in patients undergoing transcatheter aortic valve replacement?
Meta-Analysis (n=3,442)
Does periprocedural myocardial injury predict mortality and adverse events in patients undergoing transcatheter aortic valve replacement?
Odds Ratio: 4.23 (95% CI 1.95–9.19)
p-value: p=<0.001
Periprocedural myocardial injury is a strong predictor of short- and long-term mortality, neurological events, and permanent pacing following TAVR.
No takes yet. Share an insight, caveat, or question.
May warrant enhanced post-TAVR monitoring; extends meta-analytic evidence on mortality risk but leaves causal impact of prevention open.
Michail et al. (2018) conducted a meta-analysis in Transcatheter aortic valve replacement (TAVR) (n=3,442). Periprocedural myocardial injury (PPMI) vs. No periprocedural myocardial injury was evaluated on 30-day all-cause mortality (OR 4.23, 95% CI 1.95-9.19, p=<0.001). Periprocedural myocardial injury following TAVR was associated with a significantly increased risk of 30-day all-cause mortality (OR 4.23; 95% CI 1.95-9.19; P<0.001).
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