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Injections of increasing doses of estrone to male rats for the first 30 days of postnatal life brought about an inhibition of spermatogenesis and a marked atrothe last estrogen injection. Zona glomerulosa of the adrenal cortex was enlarged. In the pituitary anterior lobe gonadotrophs were seldom found and castration cells were never encountered.
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Yasumasa Arai (1964) studied this question.
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