Key result
Pulmonary leiomyoma presents with significant clinical heterogeneity, ranging from a small tracheal nodule causing chronic cough to widespread metastatic lung nodules.
Why the study?
Pulmonary leiomyoma presents with a diverse clinical spectrum, leading to complexity in establishing standardized diagnostic and therapeutic protocols.
Case Report (n=2)
Pulmonary leiomyoma presents with significant clinical heterogeneity, complicating standardized diagnostic and therapeutic protocols.
Diverse pulmonary leiomyoma presentations may complicate diagnosis; leaves open larger studies to guide evaluation.
Pulmonary leiomyoma has a diverse clinical spectrum of disease. Here we describe two patients with vastly different presentations. The first case is a 23-year-old female with a chronic cough and no visible tracheal lesion on computer tomography (CT) chest imaging. Flexible bronchoscopy revealed a small tracheal nodule, with histopathology confirming pulmonary leiomyoma. The second case is a 57-year-old female with a painless abdominal mass. CT imaging revealed widespread lung 'cannonball' nodules. Percutaneous biopsy confirmed metastatic leiomyoma. After progression on surveillance and endocrine therapy, she was commenced on doxorubicin with interval radiological improvement. These cases highlight the clinical heterogeneity in this disease, and thus, complexity in devising standardized diagnostic and therapeutic protocols.
No takes yet. Share an insight, caveat, or question.
Nair et al. (2023) conducted a case report in Pulmonary leiomyoma (n=2). Pulmonary leiomyoma presents with significant clinical heterogeneity, ranging from a small tracheal nodule causing chronic cough to widespread metastatic lung nodules.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: