Clinical Studies in Acidosis and Alkalosis; Use and Abuse of Alkali in States of Bicarbonate Deficiency Due to Renal Acidosis and Sulfanilamide Alkalosis

Article1 December 1939CLINICAL STUDIES IN ACIDOSIS AND ALKALOSIS; USE AND ABUSE OF ALKALI IN STATES OF BICARBONATE DEFICIENCY DUE TO RENAL ACIDOSIS AND SULFANILAMIDE ALKALOSISALEXIS F. HARTMANN, M.D.ALEXIS F. HARTMANN, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-13-6-940 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptFor quite some time we have been impressed with the value of alkali administration in the form of sodiumr-lactate, not only as an emergency measure in relieving acutely developing acidosis in subjects with severe diarrhea, uncontrolled diabetes, or severe renal insufficiency, but also as a means of preventing the development or recurrence of severe acidosis in patients with renal defects not so severe as to be otherwise incompatible with fairly normal life. The purpose of this paper is threefold: (1) To review experiences with some patients in whom the renal lesion progressed to a fatal degree and to point...Bibliography1. SCHOENTHALBURPEE LC: Renal rickets, Am. Jr. Dis. Child., 1930, xxxix, 517. Google Scholar2. HASTINGSSTEINHAUS ABAH: A new chart for the interpretation of acid base changes and its application to exercise, Am. Jr. Physiol., 1931, xcvi, 538. CrossrefGoogle Scholar3. BASMANPERLEY JAM: Report of patients treated with sulfanilamide at the St. Louis Children's Hospital, Jr. Pediat., 1937, xi, 212. CrossrefGoogle Scholar4. HARTMANNPERLEYBARNETT AFAMHL: A study of some of the physiological effects of sulfanilamide. I. Changes in the acid base balance, Jr. Clin. Invest., 1938, xvii, 465. CrossrefGoogle Scholar5. SOUTHWORTH H: Acidosis associated with the administration of para amino benzene sulfonamide (prontylin), Proc. Soc. Exper. Biol. and Med., 1937, xxxvi, 58. CrossrefGoogle Scholar6. LONGBLISS PHEA: The use of para amino benzene sulphonamide (sulfanilamide) or its derivatives in the treatment of infections due to beta hemolytic streptococci, pneumococci and meningococci, So. Med. Jr., 1937, xxx, 479. LONG, P. H., BLISS, E. A., and FEINSTONE, W. H.: Mode of action, clinical use and toxic manifestations of sulfanilamide, Jr. Am. Med. Assoc., 1939, cxii, 115. CrossrefGoogle Scholar7. BROWNBANNICK AEEG: The use of sulfanilamide and prontosil solution, Proc. Staff Meet. Mayo Clin., 1937, xii, 644. Google Scholar8. MARSHALL EK: Determination of sulfanilamide in blood and urine, Proc. Soc. Exper. Biol. and Med., 1937, xxxvi, 422. CrossrefGoogle Scholar9. COGGESHALLBAUER HCW: The treatment of gonorrheal and rheumatoid arthritis with sulfanilamide, New England Jr. Med., 1939, ccxx, 85. CrossrefGoogle Scholar10. HELMHOLZ HF: A comparison of mandelic acid and sulfanilamide as urinary antiseptics, Jr. Am. Med. Assoc., 1937, cix, 1039. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: St. Louis, Missouri*Read at the New Orleans meeting of the American College of Physicians March 29, 1939.From the Department of Pediatrics, Washington University School of Medicine, and the St. Louis Children's Hospital. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byDisorders of Proton Secretion by the KidneyDisorders of Proton Secretion by the KidneyAcidosis and growth in nonuremic renal diseaseDistal renal tubular acidosis in infancy: A bicarbonate wasting stateRenal acidosisRenal bedingte Störungen des Calcium- und Phosphatstoffwechsels. Renale OsteopathienRenal Acid-Base Disorders: Pathogenesis and ManagementLactate metabolismI. Growth disorders associated with renal acidosisThe Prognosis of Idiopathic Renal Acidosis in Infancy with Observations on Urine Acidification and Ammonia Production in ChildrenObservations on the pathogenesis of renal tubular acidosisIdiopathic hyperchloremic renal acidosisDie glucosurische OsteopathieDie glucosurische OsteopathieRenal Hyperehloremic AcidosisNiere und HarnRenal Failure in InfancyIdiopathic Renal Acidosis in InfancyThe Response of Idiopathic Renal Acidosis to Oral Sodium LactateMarasmus TodayIdiopathic Renal Acidosis in InfancyNeuere Entwicklungen auf dem Gebiete der Patho-Physiologie der NiereChronic Acidosis in Infants due to Renal Tubular Deficiency: Its Association with Metastatic CalcificationIDIOPATHIC RENAL ACIDOSIS IN AN INFANT WITH EXCESSIVE LOSS OF BICARBONATE IN THE URINEFurther observations concerning hypofunction of the adrenals during early lifeCLOSTRIDIAL INFECTIONS IN WAR WOUNDS 1 December 1939Volume 13, Issue 6Page: 940-956KeywordsBicarbonatesChildrenDiarrheaHospital medicineLesionsPediatricsSodium ePublished: 1 December 2008 Issue Published: 1 December 1939 PDF downloadLoading ...