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Cases of rickets and osteomalacia caused by kidney tubule defects have been classified into six sub-groups according to the various disturbances of tubule function concerned. 2. The manifestations, treatment and prognosis appropriate to the sub-groups have been considered. 3. The name "tubular rickets" (or osteomalacia) is suggested for these cases of mainly tubule dysfunction in contrast to "glomerular rickets" (or osteomalacia) which might be used to distinguish cases in which defect in the glomeruli overshadows and precedes that in the tubules.
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C. E. Dent (1952) studied this question.
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