Cardiac magnetic resonance imaging in pulmonary arterial hypertension
Key result
Cardiac magnetic resonance imaging provides accurate, noninvasive prognostic information about right ventricular mass, volumes, and function in patients with pulmonary arterial hypertension.
Population
Patients with pulmonary arterial hypertension (PAH)
Design
Review
Authors
Discussion
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Implication
Supports CMR for RV monitoring in PAH; leaves open need for prospective outcome trials.
Key Points
- To evaluate the clinical utility of cardiac magnetic resonance imaging for the noninvasive assessment of right ventricular structure, function, and treatment response in pulmonary arterial hypertension.
- Narrative review evaluating cardiac magnetic resonance imaging (CMRI) capabilities alongside conventional hemodynamic monitoring modalities.
- Synthesis of published evidence regarding CMRI-derived right ventricular mass, volumes, and functional metrics as long-term prognostic biomarkers in pulmonary arterial hypertension.
- Cardiac magnetic resonance imaging accurately quantifies right ventricular mass, volumes, and function, providing key prognostic markers of long-term survival in pulmonary arterial hypertension.
- Noninvasive imaging enables serial monitoring of therapeutic efficacy and disease progression without the procedural hazards linked to repeat right heart catheterisation.
Structured PICO
P
Population
Patients with pulmonary arterial hypertension (PAH)
I
Intervention
Cardiac magnetic resonance imaging (CMRI)
CMRI is a valuable, noninvasive tool for monitoring right ventricular function and predicting long-term outcomes in patients with pulmonary arterial hypertension.
Limitations
- Higher cost and more limited availability relative to other methods
- Need for intensive and time-consuming analysis
- Requirement for significant technical support and expertise
- Incompatibility with pacemakers and infusion pumps
- Need for breath holding may be difficult for PAH patients
Cite This Study
Peacock et al. (2013) conducted a review in Pulmonary arterial hypertension. Cardiac magnetic resonance imaging (CMRI) vs. Echocardiography and right heart catheterization was evaluated. Cardiac magnetic resonance imaging provides accurate, noninvasive prognostic information about right ventricular mass, volumes, and function in patients with pulmonary arterial hypertension.