Key result
Hospitalized patients with Guillain-Barré Syndrome had significantly higher rates of autonomic dysfunction, including reversible cardiomyopathy, syncope, tachycardia, and Horner syndrome (P<0.0001).
Why the study?
What is the prevalence of autonomic dysfunction in hospitalized patients with Guillain-Barré syndrome compared to matched controls?
Population
2,587 hospitalized patients with Guillain-Barré syndrome and 10,348 non-GBS control patients matched 4:1 by…
Design
Cohort
Authors
Loading...
May prompt AD screening in GBS inpatients; extends small-series prevalence data via national inpatient analysis.
Case-Control (n=12,935)
Yes
What is the prevalence of autonomic dysfunction in hospitalized patients with Guillain-Barré syndrome compared to matched controls?
p-value: p=<0.0001
Autonomic dysfunction is prevalent in hospitalized GBS patients, commonly manifesting as gastrointestinal, electrolyte, and cardiac abnormalities, highlighting the need for early identification.
Anandan et al. (2016) conducted a case-control in Guillain-Barré Syndrome (n=12,935). Guillain-Barré Syndrome vs. Non-GBS hospitalizations was evaluated on Autonomic dysfunction manifestations (reversible cardiomyopathy, syncope, tachycardia, and Horner syndrome) (p=<0.0001). Hospitalized patients with Guillain-Barré Syndrome had significantly higher rates of autonomic dysfunction, including reversible cardiomyopathy, syncope, tachycardia, and Horner syndrome (P<0.0001).
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: