Key result
Administering fibrinolytics prior to transfer for STEMI resulted in similar median door-to-door times compared with transfer for primary PCI (128 vs 135 minutes; P=0.71).
Why the study?
Does fibrinolysis prior to transfer improve door-to-door time and clinical outcomes compared to transfer for pPCI in STEMI patients with long transfer distances?
Population
259 STEMI patients transferred to a receiving pPCI-capable center in eastern North Carolina
Comparison
Fibrinolysis prior to interhospital transfer vs Transfer for primary percutaneous coronary…
Design
Cohort
Follow-up
in-hospital
Authors
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Similar door-to-door times with pre-transfer fibrinolysis; hypothesis-generating for outcomes in long-distance STEMI, needs RCTs.
Cohort (n=259)
Yes
Does fibrinolysis prior to transfer improve door-to-door time and clinical outcomes compared to transfer for pPCI in STEMI patients with long transfer distances?
Absolute Event Rate: 128% vs 135%
p-value: p=0.71
Administering fibrinolytics prior to transfer for STEMI patients with long transfer distances does not delay transfer and is associated with lower in-hospital mortality compared to direct transfer for pPCI.
Beri et al. (2010) conducted a cohort in ST-elevation myocardial infarction (n=259). Fibrinolysis prior to transfer vs. Transfer for primary percutaneous coronary intervention (pPCI) was evaluated on Door-to-door time (p=0.71). Administering fibrinolytics prior to transfer for STEMI resulted in similar median door-to-door times compared with transfer for primary PCI (128 vs 135 minutes; P=0.71).
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