Key result
Multiple cardiac masses initially diagnosed as multicentric myxoma on echocardiography were identified as squamous cell carcinoma metastases by postoperative histopathology.
This case highlights that metastatic squamous cell carcinoma can present as multicentric cardiac masses mimicking myxoma.
Metastases should remain in the differential for presumed myxomas; extends mimics but is hypothesis-generating from Level 5 evidence.
A 54-year-old man presented with cough, breathlessness, and fatigue. Echocardiography showed multiple masses in the left atrium, right atrium, and left ventricle. The patient underwent emergency surgery with a diagnosis of multicentric myxoma. Postoperative histopathology showed squamous cell carcinoma.
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Behranwala et al. (2000) studied this question. Multiple cardiac masses initially diagnosed as multicentric myxoma on echocardiography were identified as squamous cell carcinoma metastases by postoperative histopathology.
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