Key result
Postoperative administration of tranexamic acid significantly increased the odds of aneurysm sac shrinkage after endovascular aneurysm repair (OR 6.55), as did an occluded inferior mesenteric artery and having two or fewer patent lumbar arteries.
Why the study?
Aneurysmal sac shrinkage strongly predicts favorable long-term outcomes after EVAR, but the effects of perioperative and intraoperative factors on shrinkage needed evaluation.
What perioperative and intraoperative factors influence aneurysm sac shrinkage after endovascular abdominal aortic aneurysm repair?
Observational (n=97)
No
What perioperative and intraoperative factors influence aneurysm sac shrinkage after endovascular abdominal aortic aneurysm repair?
Odds Ratio: 6.55 (95% CI 1.99–23.62)
p-value: p=0.0019
May inform adjunct selection to favor sac shrinkage; leaves open whether targeted branch occlusion or TXA improves long-term EVAR outcomes.
Objectives: The aneurysmal sac shrinkage has been reported as the strong predictor of favorable long-term outcome after endovascular aneurysm repair (EVAR). We evaluated the effects of perioperative and intraoperative factors on the aneurysm sac shrinkage.
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Aoki et al. (2023) conducted an observational in Abdominal aortic aneurysm post-EVAR (n=97). Tranexamic acid (TXA) vs. No tranexamic acid was evaluated on Aneurysm sac shrinkage ≥5 mm (OR 6.55, 95% CI 1.99-23.62, p=0.0019). Postoperative administration of tranexamic acid significantly increased the odds of aneurysm sac shrinkage after endovascular aneurysm repair (OR 6.55), as did an occluded inferior mesenteric artery and having two or fewer patent lumbar arteries.
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