Key result
Cardiac rehabilitation significantly reduced the prevalence of metabolic syndrome (reduction rate 0.25) and improved all its components, including lipid profile, blood pressure, and fasting blood sugar.
Why the study?
Does cardiac rehabilitation improve metabolic syndrome and its components in patients with cardiovascular disease?
Meta-Analysis (n=19,324)
Does cardiac rehabilitation improve metabolic syndrome and its components in patients with cardiovascular disease?
Effect estimate: reduction rate 0.25 (95% CI 0.21, 0.3)
p-value: p=<0.001
Cardiac rehabilitation significantly improves metabolic syndrome components including blood pressure, lipid profile, fasting blood sugar, and waist circumference.
CR reduces MetS prevalence and improves all components in CVD patients; extends prior CR evidence from prognosis to metabolic outcomes.
BACKGROUND: Although the effect of cardiac rehabilitation (CR) on cardiovascular disease (CVD) prognosis has been well-documented by several systematic reviews, none have focused on the effect of CR on metabolic syndrome (MetS) and its related components. Therefore, the present systematic review and meta-analysis was conducted to assess the effect of CR on MetS and its components. MATERIALS AND METHODS: PubMed, SCOPUS, Cochrane library, and Google Scholar database were searched up to February 2014 with no date and language restrictions. The random effects model was used to assess the overall effect of CR on MetS prevalence and the change in metabolic or anthropometric measures. RESULTS: value for heterogeneity <0.001, I-squared: 86.2%]. Additionally, results showed the protective role of CR on all MetS components including high density lipoprotein cholesterol [mean difference (MD): 2.13 mg/dL, 95% CI: 1.17, 3.1], triglyceride (MD: -27.45 mg/dL, 95% CI: -36.92, -17.98), systolic blood pressure (SBP) (MD: -6.20 mmHg, 95% CI: -8.41, -3.99), diastolic blood pressure (DBP) (MD: -2.53 mmHg, 95% CI: -3.64, -1.41), fasting blood sugar (FBS) (MD: -6.42 mg/dL, 95% CI: -6.85, -5.99), and waist circumference (WC) (MD: -2.25 cm, 95% CI: -3.15, -1.35). CONCLUSION: CR has resulted in improvement in MetS and its entire components, and could be considered as a useful tool for MetS patients, especially among those with CVD.
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Sadeghi et al. (2016) conducted a meta-analysis in Metabolic syndrome (n=19,324). Cardiac rehabilitation vs. Pre-rehabilitation baseline was evaluated on Metabolic syndrome prevalence reduction (reduction rate 0.25, 95% CI 0.21, 0.3, p=<0.001). Cardiac rehabilitation significantly reduced the prevalence of metabolic syndrome (reduction rate 0.25) and improved all its components, including lipid profile, blood pressure, and fasting blood sugar.
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