The Pulmonary Manifestations of Scleroderma: An Anatomic-Physiological Correlation

Case Reports1 January 1950THE PULMONARY MANIFESTATIONS OF SCLERODERMA: AN ANATOMIC-PHYSIOLOGICAL CORRELATIONDAVID M. SPAIN, M.D., ALBERT G. THOMAS, M.D.DAVID M. SPAIN, M.D., ALBERT G. THOMAS, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-32-1-152 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptDiffuse visceral changes occurring in scleroderma have been described by Lewin and Heller,1Notthafft,2Kraus,3Klemperer, et al.,4Bevans,5and Weiss et al.6In some of these cases changes have been noted in the lungs. In most of them, however, the pulmonary findings were not a prominent clinical feature. Among the more detailed reports of lung changes in scleroderma, the review by Matsui7is noteworthy. Murphy, Krainin and Gerson8reported the first case in which pulmonary changes of scleroderma were diagnosed roentgenographically during life. This was done on the basis of diffuse reticular infiltrations in the lung associated with the...Bibliography1. LewinHeller GRJ: Die Sclerodermie, 1895, A. Hirschwald, Berlin. Google Scholar2. Von Notthafft A: Neuere Arbeiten und Ansichten ueber Sklerodermie, Centralbl. f. allg. Path. 9: 870, 1898. Google Scholar3. Kraus EJ: Zur Pathogenese der diffusen Sklerodermie, Virchows Arch. f. path. Anat. 253: 710, 1924. CrossrefGoogle Scholar4. KlempererPollackBaehr PADG: Diffuse collagen disease, J. A. M. A. 119: 331-332, 1942. CrossrefGoogle Scholar5. Bevans M: Pathology of scleroderma, with special reference to the changes in the gastro-intestinal tract, Am. J. Path. 21: 25-51, 1945. MedlineGoogle Scholar6. WeissSteadWarrenBailey SEAJVOT: Scleroderma heart disease, Arch. Int. Med. 71: 749-776, 1943. CrossrefGoogle Scholar7. Matsui S: Ueber die Pathologie und Pathogenese von Sclerodermia universalis, Mitt. a. d. med. Fak. d. k. Univ. Tokyo 31: 55-116, 1924. Google Scholar8. MurphyKraininGerson JRPMJ: Scleroderma with pulmonary fibrosis, J. A. M. A. 116: 499-501, 1941. CrossrefGoogle Scholar9. Getzowa S: Cystic and compact pulmonary sclerosis in progressive scleroderma, Arch. Path. 40: 99-106, 1945. Google Scholar10. CournandBaldwin AE: Personal communication, to be published. Google Scholar11. Dostrovsky A: Progressive scleroderma of the skin with cystic sclerodermal changes of the lungs, Arch. Dermat. and Syph. 55: 1-15, 1947. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: *Received for publication April 1, 1948.From the Laboratories of Pathology, Bellevue Hospital, and Chest Division, Bellevue Hospital (Columbia University, College of Physicians and Surgeons). 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SMYTH, M.D.Progressive Systemic Sclerosis (Scleroderma)DIFFUSE INTERSTITIAL PULMONARY FIBROSIS CAMOUFLAGED BY HYPERMETABOLISM AND CARDIAC FAILURE: ANTEMORTEM DIAGNOSIS WITH BIOPSY AND CATHETERIZATION STUDIES*JACOB J. SILVERMAN, M.D., F.A.C.P., THEODORE J. TALBOT, M.D., F.A.C.P.Pulmonary Fibrosis in Generalized SclerodermaScleroderma heart diseaseDiffuse Interstitial Fibrosis of the LungsEffects of cortisone and ACTH in cases of chronic pulmonary disease with impairment of alveolar-capillary diffusionPATTERNS OF PULMONARY FIBROSIS AS RELATED TO PULMONARY FUNCTION*DAVID M. SPAIN, M.D. 1 January 1950Volume 32, Issue 1Page: 152-161KeywordsAnatomical pathologyLungsSclerodermaSurgeonsThorax ePublished: 1 December 2008 Issue Published: 1 January 1950 PDF downloadLoading ...