Key result
High glycemic index breakfast showed a trend toward increased augmentation index compared to low glycemic index breakfast, with a significant interaction by breakfast type (p < 0.05).
Why the study?
Does a high glycemic index breakfast alter postprandial vascular function compared to a low glycemic index breakfast or water in young healthy adults?
RCT (n=40)
Randomized order
Does a high glycemic index breakfast alter postprandial vascular function compared to a low glycemic index breakfast or water in young healthy adults?
p-value: p=<0.05
High glycemic index breakfasts may acutely alter postprandial vascular responses, such as augmentation index and heart rate, in young healthy adults compared to low glycemic index meals.
High- vs. low-GI breakfasts yield minimal acute vascular differences in healthy adults; extends evidence that postprandial GI effects on function may be limited.
This study aimed to evaluate the postprandial effects of high and low glycemic index (GI) breakfasts on vascular function. It was a crossover trial that included 40 young healthy adults (50% women), aged 20–40 years, who were recruited at primary care settings. They consumed three experimental breakfasts in randomized order, each one separated by a 1-week washout period: (1) control conditions (only water); (2) low GI (LGI) breakfast (29.4 GI and 1489 KJ energy); and (3) high GI (HGI) breakfast (64.0 GI and 1318 KJ energy). Blood samples were collected at 60 and 120 min after each breakfast to determine glucose and insulin levels. Vascular parameters were measured at 15 min intervals. Augmentation index (AIx) was studied as a primary outcome. Secondary outcomes comprised glucose, insulin, heart rate (HR) and pulse pressures (PPs). We found a trend toward increased AIx, HR and PPs for the HGI versus the LGI breakfast. A significant interaction between the type of breakfast consumed and all measured parameters was identified (p < 0.05) except for central PP. Stratifying data by sex, this interaction remained significant for AIx and augmentation pressure only in males (p < 0.05). In conclusion, breakfast GI could affect postprandial vascular responses in young healthy adults.
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Sánchez‐Aguadero et al. (2017) conducted an RCT in Healthy (n=40). High glycemic index (HGI) breakfast vs. Low glycemic index (LGI) breakfast and water control was evaluated on Augmentation index (AIx) (p=<0.05). High glycemic index breakfast showed a trend toward increased augmentation index compared to low glycemic index breakfast, with a significant interaction by breakfast type (p < 0.05).
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