Key result
Patients with Type II Diabetes Mellitus demonstrated significant cognitive deficits in episodic memory, verbal fluency, active memory, processing speed, and executive function compared to healthy controls.
Why the study?
Studies report mild to moderate cognitive deficits in Type II Diabetes compared to healthy populations, prompting evaluation of cognitive functions and associated clinical and demographic factors in Greek patients.
Do patients with Type II Diabetes Mellitus have worse cognitive function and quality of life compared to healthy subjects?
Population
44 patients with DM II and 28 healthy people
Comparison
Patients with DM II vs demographically equal normal subjects
Design
Comparative study
Authors
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T2DM-associated cognitive deficits may warrant screening; leaves open whether HbA1c modification alters trajectories in trials.
Cross-Sectional (n=72)
Yes
Do patients with Type II Diabetes Mellitus have worse cognitive function and quality of life compared to healthy subjects?
Effect estimate: Cohen's d > 0.8 for verbal learning and episodic memory
Type II Diabetes Mellitus is associated with significant cognitive impairment across multiple domains, which negatively impacts quality of life and is influenced by HbA1c levels.
C. Marneras (2022) conducted a cross-sectional in Type II Diabetes Mellitus (n=72). Type II Diabetes Mellitus vs. Healthy individuals was evaluated on Cognitive function differences (episodic memory, verbal fluency, active memory, mental speed of processing, executive function) (Cohen's d > 0.8 for verbal learning and episodic memory). Patients with Type II Diabetes Mellitus demonstrated significant cognitive deficits in episodic memory, verbal fluency, active memory, processing speed, and executive function compared to healthy controls.
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