Key result
The authors argue that the previously reported case of post-vaccination myocarditis was more likely Takotsubo cardiomyopathy triggered by a vaccine-related seizure.
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This letter suggests that some cases of suspected myocarditis following SARS-CoV-2 vaccination may actually be Takotsubo cardiomyopathy.
To the Editor We read with interest the article by Chow et al1 about a 45-year-old, previously healthy woman who experienced palpitations with T-wave inversions in lead III on a routine electrocardiogram 1 month after the first dose of the Moderna mRNA-1273 severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine. Two months after the first dose, she received the second dose; 1 month later, she experienced a first, witnessed, self-limiting, generalized tonic-clonic seizure, which was interpreted as convulsive syncope.1 Workup for syncope revealed multiple episodes of ventricular tachycardia, runs of sustained ventricular tachycardia lasting up to 8 minutes, and elevated troponin.1 Endomyocardial biopsy was indicative of myocarditis.1 Upon initiation of heart failure therapy and steroids, the condition resolved.1 The study is appealing but raises concerns that require discussion. We disagree that the patient had myocarditis. More likely, she experienced Takotsubo cardiomyopathy (TTC) triggered by a...
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Finsterer et al. (2022) conducted a letter in Suspected myocarditis / Takotsubo cardiomyopathy (n=1). Moderna mRNA-1273 SARS-CoV-2 vaccine was evaluated on Diagnosis of cardiac complication. The authors argue that the previously reported case of post-vaccination myocarditis was more likely Takotsubo cardiomyopathy triggered by a vaccine-related seizure.
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