Key result
In adults with congenital heart disease and infective endocarditis, overall in-hospital mortality was 10.5% and was significantly associated with a non-surgical approach (OR 5.06; p=0.003).
Why the study?
Congenital heart disease increases infective endocarditis risk, but lesion-specific and mortality risk data were lacking.
Population
96 adult CHD patients with 105 proven and probable infective endocarditis episodes
Design
Retrospective cohort study
Follow-up
Mean 15.8 ± 10.9 years
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Requires intensive HF monitoring in adult CHD endocarditis; observational data leaves open surgical survival benefit.
Cohort (n=96)
No
Odds Ratio: 5.06
p-value: p=0.003
Infective endocarditis in adult CHD patients carries a 10.5% in-hospital mortality and frequently occurs in patients with VSD or bicuspid aortic valves, challenging current prophylaxis guidelines.
A 2022 study conducted a cohort in Infective endocarditis in adult congenital heart disease (n=96). Non-surgical approach vs. Surgical approach was evaluated on In-hospital mortality (OR 5.06, p=0.003). In adults with congenital heart disease and infective endocarditis, overall in-hospital mortality was 10.5% and was significantly associated with a non-surgical approach (OR 5.06; p=0.003).
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