Key result
Congenital heart defects in children and adolescents were associated with an infective endocarditis incidence of 2.2 per 10,000 person-years and an 8% IE-related mortality.
Population
Children and adolescents with congenital heart defects born in Norway between 1994 and 2016, drawn from a…
Design
Cohort
Follow-up
mean 12.4 years (±5.5 years)
Authors
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Contemporary cohort data quantify IE risk in pediatric CHD; leaves open optimal prevention strategies for severe defects post-intervention.
Cohort (n=1,357,543)
Yes
Infective endocarditis in children with congenital heart defects has an incidence of 2.2 per 10,000 person-years and an 8% mortality rate, strongly associated with severe defects and recent cardiac interventions.
Jortveit et al. (2018) conducted a cohort in Congenital heart defects and infective endocarditis (n=1,357,543). Congenital heart defects vs. General population was evaluated on Incidence of infective endocarditis. Congenital heart defects in children and adolescents were associated with an infective endocarditis incidence of 2.2 per 10,000 person-years and an 8% IE-related mortality.
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