Key result
Intravenous infusion of terbutalin in pregnant women with premature labor increased cardiac output and decreased total peripheral resistance with slight variation in arterial blood pressure.
Why the study?
Does intravenous infusion of terbutalin affect cardiac output and peripheral resistance in normotensive pregnant women with imminent premature labor?
Does intravenous infusion of terbutalin affect cardiac output and peripheral resistance in normotensive pregnant women with imminent premature labor?
Intravenous terbutalin increases cardiac output and decreases peripheral resistance without significantly altering blood pressure in pregnant women, suggesting safety in hypotensive patients.
Answers are grounded in this paper and cite their sources.
Terbutaline infusion may be hemodynamically tolerated in normotensive preterm labor; leaves open effects in hypotensive patients and requires prospective confirmation.
Terbutalin, a beta-mimetic drug, appears to have a favorable beta 2:beta 1 ratio. It is suitable for uterine relaxation. Ten normotensive pregnant women with imminent premature labor were studied during intravenous infusion of terbutalin with the non-invasive method of quantitative sphygmometry. Cardiac output increased and total peripheral resistance decreased. As there was only slight variation in the arterial blood pressure, terbutalin is indicated especially in cases with hypotension.
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Schwarz et al. (1983) studied Imminent premature labor (n=10). Terbutalin was evaluated on Cardiac output, total peripheral resistance, and arterial blood pressure. Intravenous infusion of terbutalin in pregnant women with premature labor increased cardiac output and decreased total peripheral resistance with slight variation in arterial blood pressure.
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