A rare case of chondroblastoma of the jugular foramen: Imaging and pathological features

Figures

• 

  Fig. 1. CT findings. (A-D) Three-dimensional CT images reveal multiple bone disruptions at the base of the left posterior cranial fossa, including the clivus, petrous apex, vertebrae, temporal bone, and hypoglossal canal. These areas show varying degrees of involvement, uneven density, unclear borders, and measure approximately 3.2 × 4.4 cm.

• 

  Fig. 2. MRI findings. T1WI and T2WI depict an irregular mass in the left jugular foramen region with adjacent bone intensity alterations. The lesion exhibits low and slightly low intensities, and there is compression of the adjacent left cerebellar hemisphere (A, B). T2 fat suppression sequences reveal low intensity within the lesion with hyperintense spots (C); T1WI enhancement scans demonstrate significant heterogeneous enhancement of the lesion, which encircles and invades the left internal jugular vein, accompanied by multiple bone destructions. Importantly, the lesion does not invade the adjacent brain parenchyma (D-F).

• 

  Fig. 3. CE-MRV findings. (A-C) Display the mass occupying the left jugular foramen and invading the left internal jugular vein in axial, sagittal, and coronal views, respectively, causing narrowing and alteration of its course.

• 

  Fig. 4. Preoperative MRI findings from 1 week prior. T1WI, T2WI and T2 fat suppression sequences (A-C); T1WI enhancement (D-F).

• 

  Fig. 5. Pathologic findings (X400). (A) Numerous chondroblasts arranged in a paving-stone pattern, displaying weakly eosinophilic cytoplasm and longitudinal nuclear grooves. (B) Irregularly distributed multinucleated giant cells and chondrocyte-like stroma. (C) Characteristic chicken wire-like calcification around the tumor cells. (D) Tumor cells are S-100 positive.