Key result
Heart rate variability analysis in Guillain-Barré syndrome revealed significantly decreased high-frequency power and increased LF:HF ratio at disease peak compared to 1-year follow-up.
Why the study?
Does power spectrum analysis of heart rate variability reveal changes in cardiovascular neural regulation over time in patients with Guillain-Barré syndrome?
Population
13 patients with Guillain-Barré syndrome
Comparison
Power spectrum analysis of heart rate variability vs Follow-up values after 1 year
Design
Cohort
Follow-up
up to 1 year
Authors
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Supports transient sympathetic predominance in acute GBS; hypothesis-generating for serial HRV in autonomic risk assessment.
Cohort (n=13)
Does power spectrum analysis of heart rate variability reveal changes in cardiovascular neural regulation over time in patients with Guillain-Barré syndrome?
Spectral analysis of heart rate variability demonstrates a shift to sympathetic predominance at the height of Guillain-Barré syndrome, which normalizes over time.
Peter Flachenecker (1997) conducted a cohort in Guillain-Barré syndrome (n=13). Acute phase of Guillain-Barré syndrome vs. 1-year follow-up was evaluated on Heart rate variability (high-frequency power, low-frequency power, and LF:HF ratio). Heart rate variability analysis in Guillain-Barré syndrome revealed significantly decreased high-frequency power and increased LF:HF ratio at disease peak compared to 1-year follow-up.
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