Wilson and Cannan studied the interconversion of glutamic acid and pyrrolidonecarboxylic acid in detail by means of changes in amino nitrogen (l), and the system so characterized was utilized by Olcott for the development of a method for the determination of glutamic acid (2).In neither case, however, were temperatures above 125" studied.We have found that glutamic acid can be converted much more rapidly at.142".Since such temperatures are known to produce profound changes in many substances, an investigation of the optical rotation of this system was undertaken.
No takes yet. Share an insight, caveat, or question.
Andre C. Kibrick (1948) studied this question.