Material from 155 patients was examined for the presence of virus particles, especially those resembling murine leukemia particles. The thin-section method, applied to buffy coat cells and to biopsies, proved to be the more efficient way to find particles which could be interpreted as resembling viruslike particles. Examination of plasma pellets by the negative-staining technique occasionally revealed structures resembling virus particles. However, this technique was found misleading compared with the thin-section technique. Structures interpreted as resembling immature murine leukemia type A virus particles and in some cases mature type C particles were found in a number of patients. The possible nature of these particles is discussed.
No takes yet. Share an insight, caveat, or question.
Seman et al. (1968) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: